Interleukin Enhancer-binding Factor 3 OKDB#: 3334
 Symbols: ILF3 Species: human
 Synonyms: DRBF, MMP4, MPP4, NF90, NFAR, TCP80, DRBP76, NFAR-1, MPHOSPH4, NF-AT-90,NUCLEAR FACTOR OF ACTIVATED T CELLS, 90-KD, NF90|DOUBLE-STRANDED RNA-BINDING PROTEIN, 76-KD, DRBP76|M-PHASE PHOSPHOPROTEIN 4, MPP4, MPHOSPH4|NUCLEAR FACTOR ASSOCIATED WITH DOUBLE-STRA  Locus: 19p13.2 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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R-L INTERACTIONS   MGI

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General Comment

NCBI Summary: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
General function Nucleic acid binding, DNA binding, Transcription factor
Comment
Cellular localization Nuclear
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Ovarian function Oogenesis, Oocyte maturation
Comment Gene whose expression is detected by cDNA array hybridization: cell surface antigens, cell adhesion, receptors Rozenn Dalbiès-Tran and Pascal Mermilloda
Expression regulated by
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Ovarian localization
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Follicle stages
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Phenotypes
Mutations
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
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Related Genes
Beta
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created: 2006-07-18 10:26:37 by: Alex C Yee, hsuehlab   email: alex.c.yee@gmail.com
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last update: 2006-07-26 14:20:36 by: Alex C Yee, hsuehlab   email: alex.c.yee@gmail.com



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