squamous cell carcinoma antigen recognised by T cells 3 OKDB#: 3631
 Symbols: SART3 Species: human
 Synonyms: TIP110, KIAA0156, MGC138188, p110(nrb), RP11-13G14,  Locus: 12q24.1 in Homo sapiens


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General Comment

NCBI Summary: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
General function
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Cellular localization Nuclear
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Ovarian function
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Expression regulated by
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Ovarian localization Oocyte
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Follicle stages
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Beta
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created: 2006-10-30 16:44:26 by: Michael  Mazin, hsuehlab   email: michael@magnetosoft.com
home page: http://reprobio.stanford.edu/hsueh/
last update: 2006-10-30 16:44:28 by: Michael  Mazin, hsuehlab   email: michael@magnetosoft.com



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