Enzyme Prosaposin OKDB#: 3460
Symbols: PSAP Species: human
Synonyms: GLBA, SAP1, FLJ00245, MGC110993,SAPOSIN A, INCLUDED|SAPOSIN B, INCLUDED|SAPOSIN C, INCLUDED|SAPOSIN D, INCLUDED|SPHINGOLIPID ACTIVATOR PROTEIN 1, INCLUDED, SAP1, INCLUDED|SPHINGOLIPID ACTIVATOR PROTEIN 2, INCLUDED, SAP2, INCLUDED|CEREBROSIDE SULFATASE ACT Ovarian localization: Granulosa
Is involved in interactions with:

1)
GPR37L1, G-protein coupled receptor 37 like 1 HPMR (NOT-IN-OKDB)
Comments: GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A. 2013 Jun 4

2)
LRP1, Low-density lipoprotein receptor-related protein 1 precursor OKdb  (Ovarian localization: Granulosa)
Comments: LRP can mediate cellular uptake and lysosomal delivery of SAP precursor (Hiesberger et al. 1998).

3)
GPR37, GPR37 OKdb  (Ovarian localization: Oocyte)
  and
head_peptide HPMR (NOT-IN-OKDB)
Comments: GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A. 2013 Jun 4

Data Supplied By HPMR