| Ligand, Growth factor Insulin-like Growth Factor Ii | OKDB#: 864 |
| Symbols: | IGF2 | Species: | human |
| Synonyms: | SOMATOMEDIN A| IGF-II OVERGROWTH SYNDROME, INCLUDED| | Ovarian localization: | Granulosa, Theca, Luteal cells |
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Is involved in interactions with: 1) IGF2R, insulin-like growth factor 2 receptor OKdb (Ovarian localization: Granulosa Theca) Comments: A single receptor binds both insulin-like growth factor II and mannose-6-phosphate Science. 1988 et al . Laureys G, et al. (Genomics. 1988) cloned the IGF2 receptor and showed it to be identical to the cation-independent mannose 6-phosphate receptor (CIM6PR). 2) INSR, Insulin receptor precursor OKdb (Ovarian localization: Oocyte Granulosa Theca Luteal) Comments: Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. Dev Biol. 1997 . |
Data Supplied By HPMR